Sv: Ekvint herpesvirus typ 2?
finns hur mkt som helst om du googlar.... equine herpes virus heter det på engelska, förkortas EHV-2 eller EHV2
Equine herpesvirus type II (EHV-2) is a DNA virus belonging to the gammaherpesvirus family. This virus infects B cells and is related to other lymphotropic herpesviruses such as Epstein-Barr virus (EBV, which causes glandular fever) and human herpesvirus type 8 (HHV-8), also known as Kaposi's sarcoma herpesvirus.
EHV-2 is highly prevalent (approaching 100%) in horse populations (Borchers et al., 1999) and has been proposed to cause, or to be a predisposing factor for, a number of distinct syndromes. These include “loss of performance”, conjunctivitis (Kershaw et al., 2001) and respiratory tract disease. EHV-2 has also been suggested as a possible transactivating factor triggering or exacerbating EHV-1 or EHV-4 reactivation and disease. While the association of EHV-2 with particular diseases is subject to debate, it is clear that this virus has the potential to escape and subvert host immune responses.
Serological detection of EHV-2 is of limited use to determine the re-activation of this herpes virus. EHV-2 can remain latent in affected animals while shedding at levels adequate to infect other horses. Culture identification of EHV-2 is slow and has low sensitivity. Molecular detection of EHV-2 by PCR is the most sensitive, specific and accurate tool in assessing the infectivity of an affected horse.
Utilities:
* Confirm the disease causing agent
* Shorten the time required to confirm a clinical diagnosis of EHV-2 infection
* Ensure that horse populations are free of EHV-2
* Early prevention of spread of this virus
* Minimize personnel exposure to this virus
* Safety monitoring of biological products that derive from horses
