Lite info, som sagt har inte jag heller hittat sådär jättemycket vettigt, det finsn mest 'icke ifrågasatt reklam'.
"The main active ingredients in Devil's claw are Harpogoside and Beta sitosterol, which possess anti-inflammatory properties and create support for joint, ligament and tendon problems. Devil's claw is reported to help with joint pain while improving vitality in the joints."
Källa:
http://www.viable-herbal.com/herbdesc1/1devilsc.htm
och
"A limited clinical study carried out in Germany reported, in 1976, that devil's claw exhibited anti-inflammatory activity comparable in many respects to the well-known antiarthritic drug, phenylbutazone.
Analgesic effects were also observed along with reductions in abnormally high cholesterol and uric-acid blood levels. However, this is apparently the only study in animals or humans to demonstrate positive anti-inflammatory activity. Several investigators have tested the efficacy of devil's claw in various standard inflammation models in animals. Little or no activity was observed by any of them. This same lack of significant anti-inflammatory activity was demonstrated for harpagoside, the principal one of several iridoid glycosides occurring in devil's claw in a range of 0.1 to 3 percent.
A recent randomized, double-blind clinical trial in Germany evaluated the effects of the drug on chronic low back pain in 118 patients over four weeks. Patients in the treatment group received the equivalent of 6 g of dried tuber per day, standardized to 50 mg harpagoside. Positive, though inconclusive, results in reducing or eliminating acute attacks of low back pain were reported, prompting a call for more clinical studies.Folkloric indications that devil's claw might prove useful as an antiarthritic and antirheumatic agent have not been verified in scientific studies. It continues to be widely utilized, particularly in Europe, as an appetite stimulant and a digestive aid. The authentic herb is, however, quite expensive, and many less costly drugs are equally effective for these purposes. Devil's claw apparently lacks any appreciable toxicity and is free from side effects. Devil's claw is by no means a wonder drug for any condition."
...
"RESEARCH
Anti-inflammatory - French research (1992) indicated that devil's claw is anti-inflammatory, but opinion is divided on its effectiveness in practice.
Pain relief - There is some evidence to confirm devil claw's use as an analgesic, since it seems to be effective in easing the symptoms of joint pain.
Bitter - The strongly bitter action of devil's claw stimulates and tones the digestive system. Many arthritic conditions are associated with poor digestion and absorption of food, and the stimulant effect of this herb on the stomach and gallbladder contributes to its overall therapeutic value as an antiarthritic remedy.
CONSTITUENTS
Devils claw contains harpagoside, harpagide, procumbine."
...
SIDE EFFECTS
Because devil's claw promotes stomach acid, anyone with gastric or duodenal ulcers should not use the herb."
Källa:
http://www.herbs2000.com/herbs/herbs_devils_claw.htm
Dessa två (ovastående) länkar måste läsas med kritisk granskning då de 'i förbifarten' nämner negativa utfall av studier ang antiinflammtorisk effekt av DK, men i nästa andetag lovordar det *s* Men som sagt, det finns lite intressant där.
Jag har inte lyckats hitta någon av de tre studier som nämns ganska frekvent när man söker på djävulsklo. Däremot så den i Tyskland på 70-talet var LITEN. Den enda större som gjorts var en franska.
"The main active ingredients in Devil's claw are Harpogoside and Beta sitosterol, which possess anti-inflammatory properties and create support for joint, ligament and tendon problems. Devil's claw is reported to help with joint pain while improving vitality in the joints."
Källa:
http://www.viable-herbal.com/herbdesc1/1devilsc.htm
och
"A limited clinical study carried out in Germany reported, in 1976, that devil's claw exhibited anti-inflammatory activity comparable in many respects to the well-known antiarthritic drug, phenylbutazone.
Analgesic effects were also observed along with reductions in abnormally high cholesterol and uric-acid blood levels. However, this is apparently the only study in animals or humans to demonstrate positive anti-inflammatory activity. Several investigators have tested the efficacy of devil's claw in various standard inflammation models in animals. Little or no activity was observed by any of them. This same lack of significant anti-inflammatory activity was demonstrated for harpagoside, the principal one of several iridoid glycosides occurring in devil's claw in a range of 0.1 to 3 percent.
A recent randomized, double-blind clinical trial in Germany evaluated the effects of the drug on chronic low back pain in 118 patients over four weeks. Patients in the treatment group received the equivalent of 6 g of dried tuber per day, standardized to 50 mg harpagoside. Positive, though inconclusive, results in reducing or eliminating acute attacks of low back pain were reported, prompting a call for more clinical studies.Folkloric indications that devil's claw might prove useful as an antiarthritic and antirheumatic agent have not been verified in scientific studies. It continues to be widely utilized, particularly in Europe, as an appetite stimulant and a digestive aid. The authentic herb is, however, quite expensive, and many less costly drugs are equally effective for these purposes. Devil's claw apparently lacks any appreciable toxicity and is free from side effects. Devil's claw is by no means a wonder drug for any condition."
...
"RESEARCH
Anti-inflammatory - French research (1992) indicated that devil's claw is anti-inflammatory, but opinion is divided on its effectiveness in practice.
Pain relief - There is some evidence to confirm devil claw's use as an analgesic, since it seems to be effective in easing the symptoms of joint pain.
Bitter - The strongly bitter action of devil's claw stimulates and tones the digestive system. Many arthritic conditions are associated with poor digestion and absorption of food, and the stimulant effect of this herb on the stomach and gallbladder contributes to its overall therapeutic value as an antiarthritic remedy.
CONSTITUENTS
Devils claw contains harpagoside, harpagide, procumbine."
...
SIDE EFFECTS
Because devil's claw promotes stomach acid, anyone with gastric or duodenal ulcers should not use the herb."
Källa:
http://www.herbs2000.com/herbs/herbs_devils_claw.htm
Dessa två (ovastående) länkar måste läsas med kritisk granskning då de 'i förbifarten' nämner negativa utfall av studier ang antiinflammtorisk effekt av DK, men i nästa andetag lovordar det *s* Men som sagt, det finns lite intressant där.
Jag har inte lyckats hitta någon av de tre studier som nämns ganska frekvent när man söker på djävulsklo. Däremot så den i Tyskland på 70-talet var LITEN. Den enda större som gjorts var en franska.